Symmetrization

Symmetrize (Not available in Mnova Lite):

This function, used in homonuclear correlation spectroscopy, replaces all signals which are symmetrically positioned about the diagonal by the smaller of the two signals. In this way unsymmetrically positioned noise and artifacts are removed. This technique should be used with caution since any symmetrical noise or artifacts will be preserved and may be mistaken for genuine signals. The data can be cleaned up considerably by using this tool in square data sets (homonuclear experiments).

There are three modes available:

Cosy-like mode

The most common type of symmetrization is performed on COSY type data where cross-peaks are symmetric on either side of a diagonal. This type of symmetrization is performed by following the menu 'Processing/More Processing/Symmetrize/Cosy-like'. The command replaces the larger of two symmetrical points with a point that has the same magnitude as the smaller one. The user must know that this kind of symmetrization must not be used on phase sensitive data (because of the potential introduction of distortions to the cross peaks).

J-Resolved mode

For J-Resolved type data where the spectrum is symmetric on both sides of a horizontal line running through the middle of the matrix. The data point with the larger magnitude is replaced by one which has a magnitude equal to that of the smaller data point. This command is available by following the menu 'Processing/More Processing/Symmetrize/J-Resolved'.

J-Resolved Sensitivity Enhancement mode

For the new Sensitivity-Enhanced J-resolved experiments by a symmetry-based spectral self-combination procedure. With this new method the symmetry of cross-peaks along the horizontal F1=0 axis allows a success spectral data self-combination after reversing the F1 dimension. Signal-to noise ratio gains of 41% can be achieved without sacrificing resolution or spectral quality.